Engineered neural tissue for peripheral nerve repair
نویسندگان
چکیده
منابع مشابه
Engineered neural tissue for peripheral nerve repair.
A new combination of tissue engineering techniques provides a simple and effective method for building aligned cellular biomaterials. Self-alignment of Schwann cells within a tethered type-1 collagen matrix, followed by removal of interstitial fluid produces a stable tissue-like biomaterial that recreates the aligned cellular and extracellular matrix architecture associated with nerve grafts. S...
متن کاملTissue-engineered Peripheral Nerve
Nerve injuries occur by a variety of mechanisms, including traumatic wounds, thermal or chemical damage, myelin or axonal degeneration, and acute compression. These injuries typically result in the loss of motor function, sensory function, or both. Functional recovery is regained upon complete axonal regeneration, which includes remyelination and reinnervation (i.e., synapse formation) of the a...
متن کاملA 3D-engineered porous conduit for peripheral nerve repair
End-to-end neurorrhaphy is the most commonly used method for treating peripheral nerve injury. However, only 50% of patients can regain useful function after treating with neurorrhaphy. Here, we constructed a 3D-engineered porous conduit to promote the function recovery of the transected peripheral nerve after neurorrhaphy. The conduit that consisted of a gelatin cryogel was prepared by molding...
متن کاملUniversity ’ s repository of research publications and other research outputs Engineered neural tissue for peripheral nerve repair
A new combination of tissue engineering techniques provides a simple and effective method for building aligned cellular biomaterials. Self-alignment of Schwann cells within a tethered type-1 collagen matrix, followed by removal of interstitial fluid produces a stable tissue-like biomaterial that recreates the aligned cellular and extracellular matrix architecture associated with nerve grafts. S...
متن کاملThe Open University ’ s repository of research publications and other research outputs Engineered neural tissue for peripheral nerve repair
A new combination of tissue engineering techniques provides a simple and effective method for building aligned cellular biomaterials. Self-alignment of Schwann cells within a tethered type-1 collagen matrix, followed by removal of interstitial fluid produces a stable tissue-like biomaterial that recreates the aligned cellular and extracellular matrix architecture associated with nerve grafts. S...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2013
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2013.06.025